Abstract
Introduction: In our study, we aimed to examine the relationship between depression and dementia, which are the most common prodromal and terminal symptoms in Parkinson’s disease.
Materials and Methods: Patients with Parkinson’s disease who presented to the Neurology outpatient clinic were evaluated on selected from October 2020 and February 2021. A total of 87 patients with Hoehn and Yahr stage 1-4 were included in the study. Of the Parkinson’s patients, 37 were female and 50 were male. Hamilton Depression Rating Scale for depression and Mini-Mental Test score was used for dementia.
Results: The duration of the disease did not make a significant difference between the sexes in depression and dementia. In contrast to dementia in the descriptive statistics according to the H-Y stage, depression is observed at all stages of Hoehn and Yahr. In Parkinson’s disease, dementia is more common in advanced-stage patients, which is associated with the course of the disease. According to the HAM-D scale, the mean depression values were 21 in male patients and 19 in female patients. Mean dementia in men and women was 22 according to the MMSE scale.
Conclusion: Depression and dementia are important determinants of the poor health-related quality of life in Parkinson’s disease. Patients should be provided with the best treatment via a multidisciplinary team.

Key words: Parkinson disease, depression, dementia