Hemolytic Uremic Syndrome: Single Centre Experience

Can Huzmeli; Hatice Terzi; Ferhan Candan; Meryem Timucin; Ayse Seker; Mehmet Sencan; Mansur Kayatas

doi:10.5455/umj.20180304114653

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Ulutas Med J. 2018; 4(1): 12-18

doi: 10.5455/umj.20180304114653

Hemolytic Uremic Syndrome: Single Centre Experience

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas.

Abstract
Introduction: Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. In this study, we aimed to evaluate patients diagnosed with HUS in our clinic.
Method: Patients who were diagnosed with HUS as clinic and laboratory between August 2012 and October 2017 were included in our nephrology clinic. Biochemistry, haemogram, ANA, anti-Ds DNA, p-ANCA, c-ANCA, anti-GBM antibody, C3, C4 of patients were studied. In some cases, ADAMTS13 was studied and renal biopsy was performed. The demographic features, clinics, and treatments of our cases were reviewed.
Results: A total of 18 patients were enrolled in the study, the average age of the patients was 48.3 (21-82) and 10 of the cases were female and 8 of the cases were male. Among the etiologic causes of HUS in patients; the complement factor B mutation, complement factor H polymorphism, breast cancer, herbal medicine, infections and idiopathic were detected. Primer glomerulonephritis was detected in 6 cases of renal biopsy.
Conclusion: Clinical and laboratory remission was obtained in 13 patients. End-stage renal failure developed in 3 of our patients.

Key words: Acute kidney damage, Hemolytic anemia, thrombocytopenia, eculizumab

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How to Cite this Article

Pubmed Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. Hemolytic Uremic Syndrome: Single Centre Experience. Ulutas Med J. 2018; 4(1): 12-18. doi:10.5455/umj.20180304114653

Web Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. Hemolytic Uremic Syndrome: Single Centre Experience. https://www.ulutasmedicaljournal.com/?mno=292623 [Access: March 25, 2023]. doi:10.5455/umj.20180304114653

AMA (American Medical Association) Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. Hemolytic Uremic Syndrome: Single Centre Experience. Ulutas Med J. 2018; 4(1): 12-18. doi:10.5455/umj.20180304114653

Vancouver/ICMJE Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. Hemolytic Uremic Syndrome: Single Centre Experience. Ulutas Med J. (2018), [cited March 25, 2023]; 4(1): 12-18. doi:10.5455/umj.20180304114653

Harvard Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas (2018) Hemolytic Uremic Syndrome: Single Centre Experience. Ulutas Med J, 4 (1), 12-18. doi:10.5455/umj.20180304114653

Turabian Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. 2018. Hemolytic Uremic Syndrome: Single Centre Experience. THE ULUTAS MEDICAL JOURNAL, 4 (1), 12-18. doi:10.5455/umj.20180304114653

Chicago Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas. "Hemolytic Uremic Syndrome: Single Centre Experience." THE ULUTAS MEDICAL JOURNAL 4 (2018), 12-18. doi:10.5455/umj.20180304114653

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Can Huzmeli, Hatice Terzi, Ferhan Candan, Meryem Timucin, Ayse Seker, Mehmet Sencan, Mansur Kayatas (2018) Hemolytic Uremic Syndrome: Single Centre Experience. THE ULUTAS MEDICAL JOURNAL, 4 (1), 12-18. doi:10.5455/umj.20180304114653

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