Abstract
Introduction: Preterm premature rupture of the membranes (PPROM) is defined as spontaneous membrane rupture without the onset of labor before 37. weeks of gestation. The aim of our study is to compare pregnant women with PPROM with those with intact membranes among pregnant women with preterm labor and to evaluate adverse obstetric outcomes.
Materials and Methods: Our study was conducted by retrospectively examining the birth records of pregnant women who gave birth between 24.-37. gestational weeks in the Department of Gynecology of Okmeydani Training and Research Hospital between February 1, 2018, and December 31, 2020. PPROM (+) (n:197) and (-) (n:161) groups were compared for obstetric and perinatal outcomes.
Results: A total of 358 patients were included in our study. Mean maternal age and abortion values of the PPROM (+) group were found to be statistically significantly higher than the PPROM (-) group (p=0.031, and p=0.001, respectively). The presence of GDM, neonatal intensive care unit admissions, 1-, and 5- minute Apgar scores of ≤7 in the PPROM (+) group was found to be statistically significantly higher than the PPROM (-) group (p=0.045, p=0.0001, p= 0.0001, and p=0.0001, respectively). When adjusted for maternal age abortus (OR, 1.01; 95% CI, 1-1.04 p=0.042) and NICU admission (OR, 0.96; 95% CI, 0.94-0.99, and p=0.0001), were found to be statistically significant in multivariate risk analysis.
Conclusions: PPROM is associated with significant maternal, fetal, and neonatal risks. The approach to these patients varies depending on gestational age and maternal and fetal infection.

Key words: Adverse obstetric outcomes, Gestational diabetes mellitus ,Neonatal intensive care unit admissions, Preterm premature rupture of the membranes