E-ISSN 2149-388X | ISSN 2149-0430
 
2025, Vol: 11, Issue: 1
11 / 1Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Cover Letter
License Agreement
Title Page

Original Research 


Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy

Marek Ilzecki, Joanna Ilzecka, Stanislaw Przywara, Aneta Grabarska, Piotr Terlecki, Andrzej Stepulak, Shawn Dave, Tomasz Zubilewicz.


Cited By:1

Abstract
Introduction: Carotid endarterectomy (CEA) is the recommended surgical procedure in the prevention of ischemic stroke. However, this procedure may lead to vascular neurological complications. The aim of the study was to measure serum carnosine dipeptidase 1 (CNDP1) and ubiquitin C - terminal hydrolase L1 (UCHL1) as markers of brain damage in patients that underwent CEA due to high-grade internal carotid artery stenosis.
Material and Methods: This study included 25 patients. Blood samples were taken from the antecubital vein at three different intervals (within a 24 hour period prior to CEA, 12 hours following surgery, and 48 hours after surgery). Serum CNDP1 and UCHL1 levels were measured by a commercially available enzyme-linked immunosorbent assay (ELISA).
Results: The study showed that serum CNDP1 and UCHL1 levels were significantly decreased 12 hours after CEA when compared to the level before the surgery. Furthermore, these enzymes levels were normalized 48 hours after CEA.
Conclusion: Data from our study showed that CEA significantly affects serum CNDP1 and UCHL1 levels. Moreover, these enzyme levels seems to reflect a brain ischemia resulting from severe internal carotid artery stenosis in patients undergoing CEA.

Key words: Carnosine dipeptidase 1, carotid endarterectomy, ischemic stroke, ubiquitin C - terminal hydrolase L1


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Marek Ilzecki
Articles by Joanna Ilzecka
Articles by Stanislaw Przywara
Articles by Aneta Grabarska
Articles by Piotr Terlecki
Articles by Andrzej Stepulak
Articles by Shawn Dave
Articles by Tomasz Zubilewicz
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Ilzecki M, Ilzecka J, Przywara S, Grabarska A, Terlecki P, Stepulak A, Dave S, Zubilewicz T. Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. Ulutas Med J. 2016; 2(3): 132-137. doi:10.5455/umj.20160713014033

Web Style

Ilzecki M, Ilzecka J, Przywara S, Grabarska A, Terlecki P, Stepulak A, Dave S, Zubilewicz T. Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. https://www.ulutasmedicaljournal.com/?mno=230870 [Access: March 15, 2025]. doi:10.5455/umj.20160713014033

AMA (American Medical Association) Style

Ilzecki M, Ilzecka J, Przywara S, Grabarska A, Terlecki P, Stepulak A, Dave S, Zubilewicz T. Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. Ulutas Med J. 2016; 2(3): 132-137. doi:10.5455/umj.20160713014033


Vancouver/ICMJE Style

Ilzecki M, Ilzecka J, Przywara S, Grabarska A, Terlecki P, Stepulak A, Dave S, Zubilewicz T. Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. Ulutas Med J. (2016), [cited March 15, 2025]; 2(3): 132-137. doi:10.5455/umj.20160713014033


Harvard Style

Ilzecki, M., Ilzecka, . J., Przywara, . S., Grabarska, . A., Terlecki, . P., Stepulak, . A., Dave, . S. & Zubilewicz, . T. (2016) Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. Ulutas Med J, 2 (3), 132-137. doi:10.5455/umj.20160713014033


Turabian Style

Ilzecki, Marek, Joanna Ilzecka, Stanislaw Przywara, Aneta Grabarska, Piotr Terlecki, Andrzej Stepulak, Shawn Dave, and Tomasz Zubilewicz. 2016. Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. THE ULUTAS MEDICAL JOURNAL, 2 (3), 132-137. doi:10.5455/umj.20160713014033


Chicago Style

Ilzecki, Marek, Joanna Ilzecka, Stanislaw Przywara, Aneta Grabarska, Piotr Terlecki, Andrzej Stepulak, Shawn Dave, and Tomasz Zubilewicz. "Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy." THE ULUTAS MEDICAL JOURNAL 2 (2016), 132-137. doi:10.5455/umj.20160713014033


MLA (The Modern Language Association) Style

Ilzecki, Marek, Joanna Ilzecka, Stanislaw Przywara, Aneta Grabarska, Piotr Terlecki, Andrzej Stepulak, Shawn Dave, and Tomasz Zubilewicz. "Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy." THE ULUTAS MEDICAL JOURNAL 2.3 (2016), 132-137. Print. doi:10.5455/umj.20160713014033


APA (American Psychological Association) Style

Ilzecki, M., Ilzecka, . J., Przywara, . S., Grabarska, . A., Terlecki, . P., Stepulak, . A., Dave, . S. & Zubilewicz, . T. (2016) Serum Carnosine Dipeptidase 1 and Ubiquitin C - Terminal Hydrolase L1 as Markers of Brain Damage in Patients After Carotid Endarterectomy. THE ULUTAS MEDICAL JOURNAL, 2 (3), 132-137. doi:10.5455/umj.20160713014033


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About THE ULUTAS MEDICAL JOURNAL

The Ulutas Medical Journal (UMJ) is a 3 monthly (quarterly), open access, double-blind peer-reviewed, an international journal. Writing a research pap ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information


Journal Owner
HAYRİYE ZEHRA ULUTAŞ
Phone: +90 (532) 165 96 39​
E-mail: zehrakenanoglu@hotmail.com​
Address: Alaattin Mah. 30. Ada sok. D11 Blok
No:4 Gungor Uydukent Sitesi  Antakya/HATAY

Editor-In-Chief
KEMAL TURKER ULUTAS, MD, Assc. Prof.
Phone: + 90 (555) 491 35 59​
E-mail: drkemalturker@gmail.com
Address: Alaattin Mah. 30. Ada sok. D11 Blok
No:4 Gungor Uydukent Sitesi  Antakya/HATAY

Publisher Information
SCOPEMED Publishing Co. - TURKEY​
E-mail: scopemed@scopemed.org
Web: https://www.scopemed.com/

 

We welcome your submissions, suggestions, comments, or questions. To reach us, please use one of the methods provided on this page or Email us at ulutasmedicaljournal@gmail.com​

We will respond within 48 to 72 hours.