E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study

Mehmet Taskiran.

Abstract
Introduction: The escalating rate of infertility, especially with many of its causes remaining enigmatic, necessitates advanced investigative measures. This study explores the correlation between various biochemical, hormonal, hematological, and oxidative stress parameters in infertile male patients and their sperm parameters.
Materials and Methods: From January to July 2023, blood samples of infertile male patients from our outpatient clinic were examined for aforementioned parameters. Patients were categorized into four groups based on their sperm parameters: Group 1 (Normal), Group 2 (Asthenospermia), Group 3 (Oligospermia), and Group 4 (Azoospermia).
Results: Infertility duration, FSH, LH, prolactin, and testicular volume (both left and right) varied significantly among the groups (p<0.01). Significant differences were also noted in monocyte, eosinophil, TAS, TOS, OSI, CRP, and ESR levels (p<0.01). Specifically, azoospermia positively correlated with increased Monocyte, TOS, OSI, CRP, and ESR levels (p-values and correlation coefficients ranging from p=0.012, r: 0.141 to p<0.001, r: 0.551). Logistic regression pinpointed TAS, TOS, OSI, and ESR as significant differentiation risk factors. According to ROC analysis, these factors were critical prognosticators for azoospermia.
Conclusion: Elevated TOS and OSI, coupled with decreased TAS levels, were linked to monocytes, CRP, and ESR in azoospermia. Thus, TAS, TOS, OSI, and ESR can be pivotal diagnostic tools for infertility, and their evaluation from routine blood samples could streamline the diagnosis and treatment response assessment of infertility.

Key words: Infertility, Azoospermia, Oxidative stress, Antioxidant, ESR, Monocyte


 
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Pubmed Style

Mehmet Taskiran. Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. Ulutas Med J. 2023; 9(3): 165-172. doi:10.5455/umj.20230815053224


Web Style

Mehmet Taskiran. Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. https://www.ulutasmedicaljournal.com/?mno=165447 [Access: December 05, 2023]. doi:10.5455/umj.20230815053224


AMA (American Medical Association) Style

Mehmet Taskiran. Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. Ulutas Med J. 2023; 9(3): 165-172. doi:10.5455/umj.20230815053224



Vancouver/ICMJE Style

Mehmet Taskiran. Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. Ulutas Med J. (2023), [cited December 05, 2023]; 9(3): 165-172. doi:10.5455/umj.20230815053224



Harvard Style

Mehmet Taskiran (2023) Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. Ulutas Med J, 9 (3), 165-172. doi:10.5455/umj.20230815053224



Turabian Style

Mehmet Taskiran. 2023. Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. THE ULUTAS MEDICAL JOURNAL, 9 (3), 165-172. doi:10.5455/umj.20230815053224



Chicago Style

Mehmet Taskiran. "Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study." THE ULUTAS MEDICAL JOURNAL 9 (2023), 165-172. doi:10.5455/umj.20230815053224



MLA (The Modern Language Association) Style

Mehmet Taskiran. "Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study." THE ULUTAS MEDICAL JOURNAL 9.3 (2023), 165-172. Print. doi:10.5455/umj.20230815053224



APA (American Psychological Association) Style

Mehmet Taskiran (2023) Investigation of Antioxidant-Oxidant Levels in Infertile Men: A Prospective Cross-Sectional Study. THE ULUTAS MEDICAL JOURNAL, 9 (3), 165-172. doi:10.5455/umj.20230815053224