E-ISSN 2149-388X | ISSN 2149-0430
 

Original Research 


The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients

Malik Abdul Jabbar Awan, Mehvish Amin, Hanan Ahmad.

Abstract
Introduction: Hepatitis B is a disease with its various complications if left untreated. Various studies have been conducted to explore the relationship between virological markers and stage of the disease. This study attempted to observe the pattern of virological markers (Hepatitis E antigen, Hepatitis B virus DNA) in Hepatitis B surface antigen positive asymptomatic patients.
Materials and Methods: This cross-sectional was conducted in liver center of Holy Family Hospital, Rawalpindi in 2016 and 349 patients who were HBsAg positive but asymptomatic were selected. Patients, with chronic hepatitis B but on current treatment were included while patients with acute hepatitis were excluded. Data about age, gender, HBeAg positive or negative and HBV DNA positive or negative was entered and analyzed using Statistical Package of Social Sciences and a descriptive analysis was performed whereas Pearsonís Chi-square test was applied at 5% level of significance to compare proportions of virological markers based on gender.
Results: Among 349 patients, 254 (73%) were males and 94 (27%) were females. HBeAg was found in 67(23.5%) patients while 218 (76.5%) were negative. The gender wise distribution of HBeAg among the females was 26.3% (20) and, among the males, it was 22.5% (49). HBV DNA was presented in 211 (65.9%) while 109 (34%) were negative for HBV DNA. Among the females, 59 (69.4%) were HBV DNA positive, as 152 (65.4%) males were positive.
Conclusion: HBV DNA was presented in more than half of the population. Virological markers (HBeAg, HBV DNA) existed almost in equal proportion among males and females.

Key words: HBsAg, HBV DNA, male, female


 
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How to Cite this Article
Pubmed Style

Awan MAJ, Amin M, Ahmad H. The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. Ulutas Med J. 2018; 4(3): 144-147. doi:10.5455/umj.20180515094138


Web Style

Awan MAJ, Amin M, Ahmad H. The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. http://www.ulutasmedicaljournal.com/?mno=299259 [Access: December 16, 2018]. doi:10.5455/umj.20180515094138


AMA (American Medical Association) Style

Awan MAJ, Amin M, Ahmad H. The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. Ulutas Med J. 2018; 4(3): 144-147. doi:10.5455/umj.20180515094138



Vancouver/ICMJE Style

Awan MAJ, Amin M, Ahmad H. The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. Ulutas Med J. (2018), [cited December 16, 2018]; 4(3): 144-147. doi:10.5455/umj.20180515094138



Harvard Style

Awan, M. A. J., Amin, . M. & Ahmad, . H. (2018) The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. Ulutas Med J, 4 (3), 144-147. doi:10.5455/umj.20180515094138



Turabian Style

Awan, Malik Abdul Jabbar, Mehvish Amin, and Hanan Ahmad. 2018. The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. THE ULUTAS MEDICAL JOURNAL, 4 (3), 144-147. doi:10.5455/umj.20180515094138



Chicago Style

Awan, Malik Abdul Jabbar, Mehvish Amin, and Hanan Ahmad. "The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients." THE ULUTAS MEDICAL JOURNAL 4 (2018), 144-147. doi:10.5455/umj.20180515094138



MLA (The Modern Language Association) Style

Awan, Malik Abdul Jabbar, Mehvish Amin, and Hanan Ahmad. "The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients." THE ULUTAS MEDICAL JOURNAL 4.3 (2018), 144-147. Print. doi:10.5455/umj.20180515094138



APA (American Psychological Association) Style

Awan, M. A. J., Amin, . M. & Ahmad, . H. (2018) The pattern of Virological Markers in Asymptomatic Hepatitis B Positive Patients. THE ULUTAS MEDICAL JOURNAL, 4 (3), 144-147. doi:10.5455/umj.20180515094138