E-ISSN 2149-388X | ISSN 2149-0430
 

Original Article 


Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals

Ibrahim Koc, Serdar Dogan.

Abstract
Introduction: The gold standard diagnostic tool for COVID-19 is real‐time reverse‐transcription polymerase chain reaction (PCR) which is not available in every healthcare institution. There is a need for faster, cheaper, and available tests. This study aimed to determine if eosinophil levels, neutrophil-lymphocyte ratio (NLR), ferritin C-reactive protein (CRP) ratio (FCR), and D-dimer to CRP ratio (DCR) can be used as biomarkers in the early diagnosis of pre-COVID-19 healthy individuals.
Materials and Methods: 289 previously healthy COVID-19 patients and 152 SARS-CoV-2 PCR negative healthy controls were included in the study. Two patient groups were compared by examining the parameters such as white blood count (WBC), neutrophil, monocyte, eosinophil, and red blood cell distribution width (RDW) obtained at the time of hospital admission before using any kind of medication.
Results: Eosinophil levels, FLR, DCR, and NLR remained significantly lower, whereas DCR, FLR, and CRP lymphocyte ratio (CLR) were found to be higher in the COVID-19 group.
Conclusion: High levels of RDW, FLR, and CLR whereas low levels of WBC, monocyte, NLR, FCR, and DCR may predict COVID-19 in patients with no comorbidities.

Key words: Ferritin lymphocyte ratio, monocyte lymphocyte ratio, COVID-19


 
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How to Cite this Article
Pubmed Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. 2022; 8(1): 51-57. doi:10.5455/umj.20211204105007


Web Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. https://www.ulutasmedicaljournal.com/?mno=39584 [Access: June 14, 2022]. doi:10.5455/umj.20211204105007


AMA (American Medical Association) Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. 2022; 8(1): 51-57. doi:10.5455/umj.20211204105007



Vancouver/ICMJE Style

Koc I, Dogan S. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J. (2022), [cited June 14, 2022]; 8(1): 51-57. doi:10.5455/umj.20211204105007



Harvard Style

Koc, I. & Dogan, . S. (2022) Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. Ulutas Med J, 8 (1), 51-57. doi:10.5455/umj.20211204105007



Turabian Style

Koc, Ibrahim, and Serdar Dogan. 2022. Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. THE ULUTAS MEDICAL JOURNAL, 8 (1), 51-57. doi:10.5455/umj.20211204105007



Chicago Style

Koc, Ibrahim, and Serdar Dogan. "Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals." THE ULUTAS MEDICAL JOURNAL 8 (2022), 51-57. doi:10.5455/umj.20211204105007



MLA (The Modern Language Association) Style

Koc, Ibrahim, and Serdar Dogan. "Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals." THE ULUTAS MEDICAL JOURNAL 8.1 (2022), 51-57. Print. doi:10.5455/umj.20211204105007



APA (American Psychological Association) Style

Koc, I. & Dogan, . S. (2022) Ferritin Lymphocyte Ratio and D-dimer C-Reactive Protein Ratio as Diagnostic Parameters in Pre-COVID-19 Healthy Individuals. THE ULUTAS MEDICAL JOURNAL, 8 (1), 51-57. doi:10.5455/umj.20211204105007