# Evaluation of Nasociliary Clearance in Covid-19 Patients

## Authors

- Muhammed Ayral ([ORCID](https://orcid.org/0000-0001-6276-8355)) — Department of Otorhinolaryngology, Dicle University, Faculty of Medicine, Diyarbakır, Turkey
- Serkan Dedeoglu ([ORCID](https://orcid.org/0000-0002-2421-4842)) — Department of Otorhinolaryngology, Yaşargil Training and Research Hospital, Diyarbakır, Turkey
- Serdar Ferit Toprak ([ORCID](https://orcid.org/0000-0003-3879-8794)) — Department of Otorhinolaryngology, Dicle University, Faculty of Medicine, Diyarbakır, Turkey

## Article information

- **Journal:** The Ulutas Medical Journal (Ulutas Med J), ISSN 2149-388X
- **Issue:** Volume 8, Issue 1 (2022), pages 45–50
- **Article type:** Original Article
- **Published online:** 2022-03-09
- **DOI:** [10.5455/umj.20211220121456](https://doi.org/10.5455/umj.20211220121456)
- **Licence:** [CC BY-NC 4.0](https://creativecommons.org/licenses/by-nc/4.0/)
- **Article page:** https://www.ulutasmedicaljournal.com/?mno=88290
- **PDF:** https://www.ulutasmedicaljournal.com/pdf/88290.pdf

## Abstract

Introduction: The new coronavirus 2019 (COVID-19), which rapidly turned into a global pandemic, progresses with mild flu-like symptoms, suggesting that there may be damage to the nasociliary clearance. The study aimed to evaluate whether nasociliary clearance in individuals with Covid-19 is affected or not using the saccharin test. Materials and Methods: Saccharin test was applied to 47 PCR positive active COVID-19, 42 recovered PCR negative COVID-19, and 42 healthy groups to evaluate their nasociliary functions and the result was calculated in minutes. Results: 42 (32.1%) recovered patients, 42 (32.1%) healthy, and 47 (35.9%) COVID-19 patients were included in the study. There were 13 women (31%), 29 men (69%) in the healthy, 18 women (42.9%), 24 men (57%) in the recovered group, 14 women (29.8%), and 33 men (70%) in the active patients. The mean times of saccharin nasociliary clearance were 24 (18-27) min in the active covid-19 patient group, 13 (8-17) min in the recovered covid-19 group, and 11 (8-13) min in the healthy. There was a difference between the groups in terms of the Saccharine test (p

## Keywords

COVID-19; nasal provocation tests; Saccharin; Smell; Upper respiratory tract infections

## How to cite

Ayral M, Dedeoglu S, Toprak SF. Evaluation of Nasociliary Clearance in Covid-19 Patients. Ulutas Med J. 2022;8(1):45-50. doi:10.5455/umj.20211220121456

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