# DRESS Syndrome Associated with Elevated Liver Enzyme and Acute Kidney Injury after Allopurinol Use

## Authors

- Seymanur Ala Enli ([ORCID](https://orcid.org/0000-0003-2568-7155)) — Ankara Yildirim Beyazit Universitesi, Ankara City Hospital, Internal Medicine Department, Ankara, Turkey
- Emin Gemcioglu ([ORCID](https://orcid.org/0000-0001-9751-8452)) — Ministry of Health Ankara City Hospital, Internal Medicine Department, Ankara, Turkey
- Merve Kiran ([ORCID](https://orcid.org/0000-0003-2498-0472)) — Ministry of Health Ankara City Hospital, Pathology Department, Ankara, Turkey

## Article information

- **Journal:** The Ulutas Medical Journal (Ulutas Med J), ISSN 2149-388X
- **Issue:** Volume 6, Issue 1 (2020), pages 44–48
- **Article type:** Case Report
- **Published online:** 2020-03-17
- **DOI:** [10.5455/umj.20200207110845](https://doi.org/10.5455/umj.20200207110845)
- **Licence:** [CC BY-NC 4.0](https://creativecommons.org/licenses/by-nc/4.0/)
- **Article page:** https://www.ulutasmedicaljournal.com/?mno=85807
- **PDF:** https://www.ulutasmedicaljournal.com/pdf/85807.pdf

## Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare, potentially life-threatening, drug-induced hypersensitivity reaction that includes skin eruption, hematologic abnormalities (eosinophilia and atypical lymphocytosis), lymphadenopathy, and internal organ involvement (liver, kidney, and lung). Moreover, retrospective studies have reported a mortality rate between 5% and 10%. In this paper, a case of DRESS with renal and hepatic organ involvement developing 2 weeks after the use of allopurinol which is among the most common drugs for DRESS will be presented.

## Keywords

Allopurinol; DRESS; Elevated liver enzyme; Acute kidney injury

## How to cite

Enli SA, Gemcioglu E, Kiran M. DRESS Syndrome Associated with Elevated Liver Enzyme and Acute Kidney Injury after Allopurinol Use. Ulutas Med J. 2020;6(1):44-48. doi:10.5455/umj.20200207110845

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