# Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital

## Authors

- Obianuju Uchenna Ilechukwu ([ORCID](https://orcid.org/0000-0001-9645-0871)) — Department of Chemical Pathology, Chukwuemeka Odumegwu Ojukwu University, Awka, Anambra State, Nigeria
- Jude Anaelechi Onuegbu ([ORCID](https://orcid.org/0000-0001-7342-9949)) — Department of Chemical Pathology, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria
- Japhet Madu Olisekodiaka ([ORCID](https://orcid.org/0000-0003-2487-1233)) — Department of Chemical Pathology, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria
- Chikaodili Nwando Obi-Ezeani ([ORCID](https://orcid.org/0000-0002-9581-0051)) — Department of Chemical Pathology, Chukwuemeka Odumegwu Ojukwu University, Awka, Anambra State, Nigeria

## Article information

- **Journal:** The Ulutas Medical Journal (Ulutas Med J), ISSN 2149-388X
- **Issue:** Volume 7, Issue 2 (2021), pages 86–91
- **Article type:** Original Article
- **Published online:** 2021-06-25
- **DOI:** [10.5455/umj.20210422011242](https://doi.org/10.5455/umj.20210422011242)
- **Licence:** [CC BY-NC 4.0](https://creativecommons.org/licenses/by-nc/4.0/)
- **Article page:** https://www.ulutasmedicaljournal.com/?mno=75583
- **PDF:** https://www.ulutasmedicaljournal.com/pdf/75583.pdf

## Abstract

Introduction: Preeclampsia is a clinical condition unique to humans which forms a major part of hypertensive disorders in pregnancy. Although its exact etiology remains unknown, an imbalance between lipid peroxides and antioxidants is implicated. The study aimed to evaluate plasma selenium, zinc, and malondialdehyde (MDA) levels in newly diagnosed preeclamptic women attending antenatal visits at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital (COOUTH), Awka in Anambra State. Materials and Methods: A total of 81 female participants were recruited and grouped into three (A, B, and C) comprising 21 newly diagnosed preeclamptic women, 30 healthy pregnant control, and 30 non-pregnant control participants respectively. Results: The newly diagnosed preeclamptics had significantly lower plasma selenium levels when compared with the healthy pregnant and non-pregnant controls (p0.05), it was however significantly lower in the preeclamptics and healthy pregnant women when compared with the non-pregnant women (p

## Keywords

Preeclampsia; Pregnancy; Selenium; Zinc; Malondialdehyde

## How to cite

Ilechukwu OU, Onuegbu JA, Olisekodiaka JM, Obi-Ezeani CN. Evaluation of Plasma Selenium, Zinc and Malondialdehyde Levels in Newly Diagnosed Preeclamptic Women at A Teaching Hospital. Ulutas Med J. 2021;7(2):86-91. doi:10.5455/umj.20210422011242

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