# Is Tolvaptan in the Treatment of SIADH Following Pituitary Surgery a Right Choice?

## Authors

- Suleyman Karakose ([ORCID](https://orcid.org/0000-0003-4680-7435)) — Department of Nephrology, Ankara Training and Research Hospital
- Ayse Zeynep Bal ([ORCID](https://orcid.org/0009-0001-8970-7082)) — Department of Nephrology, Ankara Training and Research Hospital
- Selman Unverdi ([ORCID](https://orcid.org/0000-0003-1902-2675)) — Department of Nephrology, Ankara Training and Research Hospital
- Murat Duranay ([ORCID](https://orcid.org/0000-0002-2893-4484)) — Department of Nephrology, Ankara Training and Research Hospital

## Article information

- **Journal:** The Ulutas Medical Journal (Ulutas Med J), ISSN 2149-388X
- **Issue:** Volume 2, Issue 3 (2016), pages 154–156
- **Article type:** Case Report
- **Published online:** 2016-07-25
- **DOI:** [10.5455/umj.20160703095035](https://doi.org/10.5455/umj.20160703095035)
- **Licence:** [CC BY-NC 4.0](https://creativecommons.org/licenses/by-nc/4.0/)
- **Article page:** https://www.ulutasmedicaljournal.com/?mno=232578
- **PDF:** https://www.ulutasmedicaljournal.com/pdf/232578.pdf

## Abstract

Background: Fluid and electrolyte disturbances, especially hyponatremia are common complications after pituitary surgeries. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the leading cause of hyponatremia in hospitals. Fluid restriction is the first step in treatment of SIADH. In rare cases vasopressin receptor inhibitors might be useful for medical treatment. Case Presentation: In this paper, we present a case of SIADH after a pituitary surgery with an unpredictable effect of tolvaptan. Conclusion: Tolvaptan is the most preferred agent for the treatment of SIADH nowadays. However tolvaptan might cause unpredictable situations in the course of treatment that clinicians must be very careful and in close follow up the patient.

## Keywords

Hypernatremia; hyponatremia; pituitary surgery; SIADH; tolvaptan

## How to cite

Karakose S, Bal AZ, Unverdi S, Duranay M. Is Tolvaptan in the Treatment of SIADH Following Pituitary Surgery a Right Choice?. Ulutas Med J. 2016;2(3):154-156. doi:10.5455/umj.20160703095035

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