# The Effect of Dietary Protein Quality on Short-Term Satiety and Daily Energy Intake

## Authors

- Nurgul Arslan ([ORCID](https://orcid.org/0000-0002-7618-0859)) — Nutrition and Dietetic Department, Faculty of Health Sciences, Diclel University, Diyarbakır, Turkey
- Funda Pinar Cakiroglu ([ORCID](https://orcid.org/0000-0003-2324-6874)) — Department of Nutrition and Dietetics, Faculty of Health Sciences, Ankara University, Ankara, Turkey
- Bulent Yaprak ([ORCID](https://orcid.org/0000-0001-5592-9755)) — Malatya Training and Research Hospital, Department of Internal Medicine, Malatya, Turkey

## Article information

- **Journal:** The Ulutas Medical Journal (Ulutas Med J), ISSN 2149-388X
- **Issue:** Volume 9, Issue 1 (2023), pages 13–23
- **Article type:** Original Article
- **Published online:** 2023-03-09
- **DOI:** [10.5455/umj.20221223105724](https://doi.org/10.5455/umj.20221223105724)
- **Licence:** [CC BY-NC 4.0](https://creativecommons.org/licenses/by-nc/4.0/)
- **Article page:** https://www.ulutasmedicaljournal.com/?mno=133643
- **PDF:** https://www.ulutasmedicaljournal.com/pdf/133643.pdf

## Abstract

Introduction: Some protein structures in the structure of foods are known to provide long-lasting satiety. Depending on the food source, this period of satiety can be shortened or lengthened. It has been reported that in diets for treating obesity in which long-term satiety is a goal, animal-derived proteins can help people feel fuller for longer. This study aimed to examine the effects on satiety markers after breakfast of consuming breakfast foods prepared with different protein sources. Materials and Methods: The study included 40 participants but concluded with 39 participants. Sixteen males and 23 females participated in the research. The participants in the study were randomly assigned to begin the investigation. After 12 hours of fasting, the study participants were offered two breakfasts on separate days. Two distinct breakfasts consisting of foods of animal origin and foods of vegetable origin were served. Results: The breakfasts had similar calories, protein, fat, carbohydrates, and fiber. Before and after breakfast, a VAS scale with seven satiety markers was created and applied. The scale was applied 0 minutes before breakfast, 30 minutes, 60 minutes, 120 minutes, and 180 minutes after breakfast. After breakfast, it was observed that the satiety markers of animal origin had a longer duration and higher scores than those of plant origin. Conclusion: In cases where energy restriction is necessary, it has been determined that increasing the protein quality in the foods consumed can provide long-term satiety regardless of the amount consumed.

## Keywords

Dietary protein; satiety; hunger; energy intake

## How to cite

Arslan N, Cakiroglu FP, Yaprak B. The Effect of Dietary Protein Quality on Short-Term Satiety and Daily Energy Intake. Ulutas Med J. 2023;9(1):13-23. doi:10.5455/umj.20221223105724

## References

1. Group LAR. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes: four-year results of the Look AHEAD trial. Archives of internal medicine. 2010;170(17):1566. https://doi.org/10.1001/archinternmed.2010.334
2. Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, Anton SD, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. New England Journal of Medicine. 2009;360(9):859-73. https://doi.org/10.1056/nejmoa0804748
3. Baysal A, Bozkurt N, Aksoy M. Diyet el kitabı, Hatipoğlu Yayınevi,
4. Baskı, Ankara. 2002.
5. Layman DK. Protein quantity and quality at levels above the RDA improves adult weight loss. Journal of the American College of Nutrition. 2004;23(sup6):631S-6S. https://doi.org/10.1080/07315724.2004.10719435
6. Reddy ST, Wang C-Y, Sakhaee K, Brinkley L, Pak CY. Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism. American Journal of Kidney Diseases. 2002;40(2):265-74. https://doi.org/10.1053/ajkd.2002.34504
7. Schaafsma G. The protein digestibility–corrected amino acid score. The Journal of nutrition. 2000;130(7):1865S -7S. https://doi.org/10.1093/jn/130.7.1865s
8. Franklin SS, Gordon A, Kleeman CR, Maxwell MH. Use of a balanced low-protein diet in chronic renal failure. Jama. 1967;202(6):477-84. https://doi.org/10.1001/jama.1967.03130190083011
9. Holt SH, Brand-Miller JC, Stitt PA. The effects of equal-energy portions of different breads on blood glucose levels, feelings of fullness and subsequent food intake. Journal of the American Dietetic Association. 2001;101(7):767-73. https://doi.org/10.1016/s0002-8223(01)00192-4
10. Karra E, Chandarana K, Batterham RL. The role of peptide YY in appetite regulation and obesity. The Journal of physiology. 2009;587(1):19-25. https://doi.org/10.1113/jphysiol.2008.164269
11. Stern L, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, et al. The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Annals of internal medicine. 2004;140(10):778-85. https://doi.org/10.7326/0003-4819-140-10-200405180-00007
12. Bayham BE, Greenway FL, Johnson WD, Dhurandhar NV. A randomized trial to manipulate the quality instead of quantity of dietary proteins to influence the markers of satiety. Journal of Diabetes and its Complications. 2014;28(4):547-52. https://doi.org/10.1016/j.jdiacomp.2014.02.002
13. Blatt AD, Roe LS, Rolls BJ. Increasing the protein content of meals and its effect on daily energy intake. Journal of the American Dietetic Association. 2011;111(2):290-4. https://doi.org/10.1016/j.jada.2010.10.047
14. Flint A, Raben A, Blundell J, Astrup A. Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. International journal of obesity. 2000;24(1):38. https://doi.org/10.1038/sj.ijo.0801083
15. Morell P, Fiszman S. Revisiting the role of protein-induced satiation and satiety. Food Hydrocolloids. 2017;68:199-210. https://doi.org/10.1016/j.foodhyd.2016.08.003
16. Vander Wal JS, Marth JM, Khosla P, Jen KC, Dhurandhar NV. Short- term effect of eggs on satiety in overweight and obese subjects. Journal of the American College of Nutrition. 2005;24(6):510-5. https://doi.org/10.1080/07315724.2005.10719497
17. Fallaize R, Wilson L, Gray J, Morgan LM, Griffin BA. Variation in the effects of three different breakfast meals on subjective satiety and subsequent intake of energy at lunch and evening meal. European journal of nutrition. 2013;52(4):1353-9. https://doi.org/10.1007/s00394-012-0444-z
18. Ratliff J, Leite JO, de Ogburn R, Puglisi MJ, VanHeest J, Fernandez ML. Consuming eggs for breakfast influences plasma glucose and ghrelin, while reducing energy intake during the next 24 hours in adult men. Nutrition Research. 2010;30(2):96-103. https://doi.org/10.1016/j.nutres.2010.01.002
19. Kral TV, Bannon AL, Chittams J, Moore RH. Comparison of the satiating properties of egg-versus cereal grain-based breakfasts for appetite and energy intake control in children. Eating behaviors. 2016;20:14-20. https://doi.org/10.1016/j.eatbeh.2015.11.004
20. Marsset-Baglieri A, Fromentin G, Airinei G, Pedersen C, Léonil J, Piedcoq J, et al. Milk protein fractions moderately extend the duration of satiety compared with carbohydrates independently of their digestive kinetics in overweight subjects. British Journal of Nutrition. 2014;112(4):557-64. https://doi.org/10.1017/s0007114514001470
21. Crowder CM, Neumann BL, Baum JI. Breakfast protein source does not influence postprandial appetite response and food intake in normal weight and overweight young women. Journal of nutrition and metabolism. 2016;2016. https://doi.org/10.1155/2016/6265789
22. Douglas SM, Lasley TR, Leidy HJ. Consuming Beef vs. Soy Protein Has Little Effect on Appetite, Satiety, and Food Intake in Healthy Adults, 2. The Journal of nutrition. 2015;145(5):1010-6. https://doi.org/10.3945/jn.114.206987
23. Lang V, Bellisle F, Alamowitch C, Craplet C, Bornet F, Slama G, et al. Varying the protein source in mixed meal modifies glucose, insulin and glucagon kinetics in healthy men, has weak 23 77 Dietary Protein Quality Arslan et al. effects on subjective satiety and fails to affect food intake. European journal of clinical nutrition. 1999;53(12):959. https://doi.org/10.1038/sj.ejcn.1600881
24. Veldhorst M, Smeets A, Soenen S, Hochstenbach-Waelen A, Hursel R, Diepvens K, et al. Protein-induced satiety: effects and mechanisms of different proteins. Physiology & behavior. 2008;94(2):300-7. https://doi.org/10.1016/j.physbeh.2008.01.003
25. Hu X, Gao J, Zhang Q, Fu Y, Li K, Zhu S, et al. Soy fiber improves weight loss and lipid profile in overweight and obese adults: a randomized controlled trial. Molecular nutrition & food research. 2013;57(12):2147-54. https://doi.org/10.1002/mnfr.201300159
26. Larosa JC, Fry AG, Muesing R, Rosing DR. Effects of high-protein, low-carbohydrate dieting on plasma lipoproteins and body weight. Journal of the American Dietetic Association. 1980;77(3):264-70. https://doi.org/10.1016/s1094-7159(21)03514-5
27. Layman DK, Boileau RA, Erickson DJ, Painter JE, Shiue H, Sather C, et al. A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. The Journal of nutrition. 2003;133(2):411-7. https://doi.org/10.1093/jn/133.2.411
28. Westman EC, Yancy WS, Edman JS, Tomlin KF, Perkins CE. Effect of 6-month adherence to a very low carbohydrate diet program. The American journal of medicine. 2002;113(1):30-6. https://doi.org/10.1016/s0002-9343(02)01129-4
29. Veldhorst MA, Nieuwenhuizen AG, Hochstenbach -Waelen A, van Vught AJ, Westerterp KR, Engelen MP, et al. Dose-dependent satiating effect of whey relative to casein or soy. Physiology & behavior. 2009;96(4-5):675-82. https://doi.org/10.1016/j.physbeh.2009.01.004
30. Cota D, Proulx K, Smith KAB, Kozma SC, Thomas G, Woods SC, et al. Hypothalamic mTOR signaling regulates food intake. Science. 2006;312(5775):927-30. https://doi.org/10.1126/science.1124147
31. Layman DK, Walker DA. Potential importance of leucine in treatment of obesity and the metabolic syndrome. The Journal of nutrition. 2006;136(1):319S-23S. https://doi.org/10.1093/jn/136.1.319s
32. Acheson KJ, Blondel-Lubrano A, Oguey-Araymon S, Beaumont M, Emady-Azar S, Ammon-Zufferey C, et al. Protein choices targeting thermogenesis and metabolism–. The American journal of clinical nutrition. 2011;93(3):525-34. https://doi.org/10.3945/ajcn.110.005850
33. Astrup A. The satiating power of protein—a key to obesity prevention?: Oxford University Press; 2005. https://doi.org/10.1093/ajcn/82.1.1